• Logo
  • SBMUJournals

Acute Myocardial Injury and Electrocardiogram Changes in a Case of Aluminum Phosphide Poisoning

Bita Dadpour, Nasrin Milani, Omid Mehrpour, Fares Najari




Aluminum phosphide (AIP) poisoning is one of the major causes of mortality among toxic substances. The symptoms and signs of toxicity are nonspecific and related to dose and route of exposure. A 20-year-old woman was admitted to the emergency department due to the consumption of one AIP tablet. ECG was normal at 2 hours post-ingestion and echocardiography revealed LVEF of 55-60% at 4 hours post admission. ECG abnormalities in this patient included VT and VF on the second night. She experienced an unusual rhythm disturbance in term of LBBB and Brugada pattern besides low ejection fraction of left ventricue (about 20-25%) on the third day. The main emphasis for AIP poisoning cases is on a timely, precise and prompt symptomatic treatment.


Aluminum phosphide, Poisoning, ECG changes, Acute myocardial injury


‎1.‎ Nik NM, Hawari R, Shafie H. A case report of aluminium phosphide poisoning. The Medical Journal of Malaysia. 2016; 71(4):213-‎‎4. [PMID]‎

‎2.‎ Lehoux J, Hena Z, McCabe M, Peek G. Aluminium phosphide poisoning resulting in cardiac arrest, successful treatment with ‎Extracorporeal Cardiopulmonary Resuscitation (ECPR): A case report. Perfusion. 2018; 33(7):597-8. ‎‎[DOI:10.1177/0267659118777196] [PMID]‎

‎3.‎ Mehrpour O, Jafarzadeh M, Abdollahi M. A systematic review of aluminium phosphide poisoning. Archives of Industrial Hygiene ‎and Toxicology. 2012; 63(1):61-73. [DOI:10.2478/10004-1254-63-2012-2182] [PMID]‎

‎4.‎ Meel BL. Aluminium phosphide (tank pill) poisoning in the Transkei region of South Africa: A case report. Medicine, Science and ‎the Law. 2011; 51(2):116-8. [DOI:10.1258/msl.2010.010205] [PMID]‎

‎5.‎ Dadpour B, Mokhtarpour M, Abdollahi M, Afshari R. An outbreak of aluminium phosphide poisoning in Mashhad, Iran. Arhiv za ‎Higijenu Rada i Toksikologiju. 2016; 67(1):65-6. [DOI:10.1515/aiht-2016-67-2769] [PMID]‎

‎6.‎ Singh RB, Rastogi SS, Singh DS. Cardiovascular manifestations of aluminium phosphide intoxication. The Journal of the ‎Association of Physicians of India. 1989; 37(9):590-2. [PMID]‎

‎7.‎ Akkaoui M, Achour S, Abidi K, Himdi B, Madani A, Zeggwagh AA, et al. Reversible myocardial injury associated with aluminum ‎phosphide poisoning. Clinical Toxicology. 2007; 45(6):728-31. [DOI:10.1080/15563650701517350] [PMID]‎

‎8.‎ Hirani SA, Rahman A. Aluminium phosphide poisoning: A case report. Journal of Ayub Medical College Abbottabad. 2010; ‎‎22(4):221-2. [PMID]‎

‎9.‎ Mouhaoui M, Khaleq K, Rabbai O, Yaqini K, Louardi H. [Aluminium phosphide poisoning and pregnancy (case report) (French)]. ‎Annales Françaises d'Anesthésie et de Réanimation. 2008; 27(2):181-2. [DOI:10.1016/j.annfar.2007.11.021] [PMID]‎

DOI: https://doi.org/10.32598/ijmtfm.v9i2.24274