Modified Atkins Diet for Intractable Childhood Epilepsy

Mohammad BARZEGAR, Poupak IRANDOUST, Mehrangiz EBRAHIMI MAMEGHANI

Abstract


281

Objective

The aim of the present study was to evaluate the efficacy and tolerability of a modified Atkins diet for intractable childhood epilepsy.

Materials & Methods

Twenty one children with medically intractable epilepsy were enrolled in the study. Inclusion criteria were at least four seizures per month and a trial of at least three anticonvulsants without becoming seizure-free. The subjects received the diet over a 6-month period.

Results

Three months after diet initiation, 15 patients (71.4%) remained on the diet and 12 (57.1%) had >50% seizure reduction. Eleven patients (52.4%) completed the 6-month study and 8 (38.1%) chose to remain on the diet afterward. At 6 months, 9 patients (42.8%) had >50% seizure reduction. The diet was more effective in cryptogenic epilepsy (p=0.032). Most complications were transient and successfully managed by careful follow-up and conservative strategies.

Conclusion

The modified Atkins diet is an effective and well- tolerated therapy for intractable childhood epilepsy.

 


Keywords


Atkins diet, ketogenic diet,intractable epilepsy, children

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DOI: https://doi.org/10.22037/ijcn.v4i3.2003

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