Painless Loss of Vision as The First Presentation of Undiagnosed Neurofibromatosis 1 in A Child

Siba Prosad PAUL, Shameem AHMED



How to Cite This Article: Paul SP, Ahmed S, Painless Loss of Vision as The First Presentation of Undiagnosed Neurofibromatosis 1 in A Child. Iran J Child Neurol. Autumn 2015;9(4):58-60.



A 10 year old presented with painless loss of vision as the first manifestation of neurofibromatosis 1 (NF1). Clinical assessment detected diagnostic features of NF1 and Magnetic Resonance Imaging (MRI) scan confirmed presence of plexiform neurofibroma and bilateral optic pathway glioma (OPG). The child was managed with chemotherapy which helped in improvement of vision. Review of current literature recommends vision testing in diagnosed cases of NP1 till 7 years of age; this is aimed at detecting visual impairments resulting from a symptomatic OPG.


Neurofibromatosis type 1; Visual acuity loss; Optic pathway glioma; Annual ophthalmological assessment; MRI

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