Results of Non-contrast Brain Computed Tomography Scans of 1-18 Year Old Epileptic Children
Iranian Journal of Child Neurology,
Vol. 6 No. 3 (2012),
24 September 2012
How to Cite this Article: Fallah R, Nafisi Moghadam R, Fallah Tafti M, Salmani Nodoushan M. Results of Noncontrast Brain Computed Tomography Scans of 1-18 Year Old Epileptic Children. Iran J Child Neurol 2012; 6(3): 33-38.
The advent of computed tomography (CT) scan revolutionized the diagnosticevaluation of neurologic patients. The aim of this study was to evaluate brain CTresults of epileptic children.
Materials & Methods
In a descriptive cross-sectional study, noncontrast brain CT scan of 150 consecutive1-18 year old epileptic children whom were referred to pediatric neurology clinic ofShahid Sadoughi University of Medical Sciences, from May 2008 to October 2010 inYazd-Iran, evaluated.
Sixty two girls and 88 boys with mean age of 6.6 ± 4.3 years were evaluated.In 38 (25.3 %) children, seizure onset age was under one year and 38 others hadabnormal mental / developmental status. Fifty three children (35.3 %) and 97 (64.7%)had partial and generalized seizures, respectively. Partial seizures were more prevalentin children with seizure onset in < 1 year [41.5% (22/53) vs. 16.5% (16/97)] Result of CT was normal in 74 % (n=111). Among the patients with abnormalresults, 18(46%) had brain atrophy, 10 (25.6%) structural CNS dysgenesia, six (15.4%)intracranial calcification, three (7.8%) hydrocephaly and two had (5.2%) brain tumor.Abnormal brain CT was more prevalent in patients with seizure onset in less than oneyear of age [60.5% (23 of 38) vs. 14.3% (16 of 112), p = 0.003], partial epilepsy [51% (27of 53) vs. 12% (12/97)], and abnormal developmental status [ 81.5% (31 of 38) vs.7% (8of 112]. Mean age of seizure onset in epileptic children with abnormal brain CT scanwas less (M ± SD:1/17 ± 0.6 years versus 4.02±1.9 years).
Brain CT scan might be considered in evaluation of epileptic children with partialseizures, seizure onset in less than one year of age or neurodevelopmental delay.
- Jagoda A, Gupta K. The emergency department evaluationof the adult patient who presents with a first-time seizure.Emerg Med Clin North Am 2011; 29(1):41-9.
- Camfield PR, Camfield CS. Pediatric epilepsy. In:Swaiman KF, Ashwal S, Ferriero D M. Pediatric Neurology: principles & practice. (4th ed). Philadelphia:Mosby Elsevier, 2006.P. 983.
- Gaillard WD, Chiron C, Cross JH, Harvey AS, Kuzniecky R, Hertz-Pannier L, Vezina LG; ILAE, Committee for Neuroimaging, Subcommittee for Pediatric. Guidelines for imaging infants and children with recent-onset epilepsy. Epilepsia 2009; 50(9):2147-53.
- Soto-Ares G, Jissendi Tchofo P, Szurhaj W, Trehan G,Leclerc X. Management of patients after a first seizure. J Neuroradiol 2004; 31(4):281-8. (in French)
- Hirtz D, Ashwal S, Berg A, et al. Practice parameter:evaluating a first nonfebrile seizure in children: report of the quality standards subcommittee of the American Academy of Neurology, the Child Neurology Society, and the American Epilepsy Society. Neurology 2000; 55:616– 623.
- Kuzniecky RI. Neuroimaging in pediatric epilepsy.Epilepsia 1996; 37, Suppl 1:S10-21.
- Adamsbaum C, Rolland Y, Husson B. Pediatric neuroimaging emergencies. J Neuroradiol 2004;31(4):272-80. (in French)
- Proposal for revised classification of epilepsies and epileptic syndromes. Commission on Classification and Terminology of the International League Against Epilepsy. Epilepsia 1989; 30:389–399.
- Hsieh DT, Chang T, Tsuchida TN, et al. New-onset afebrile seizures in infants: role of neuroimaging.Neurology 2010;12:74(2):150-6.
- Khodapanahandeh F, Hadizadeh H. Neuroimaging inchildren with first afebrile seizures: to order or not toorder? Arch Iran Med 2006;9(2):156-8.
- Berg AT, Testa FM, Levy SR, Shinnar S. Neuroimaging in children with newly diagnosed epilepsy: A community based study. Pediatrics 2000; 106(3):527-32.
- Maytal J, Krauss JM, Novak G, Nagelberg J, Patel M. Therole of brain computed tomography in evaluating children with new onset of seizures in the emergency department.Epilepsia 2000; 41(8):950-4.
- Kumar R, Navjivan S, Kohli N, Sharma B. Clinicalcorrelates of CT abnormality in generalized childhood epilepsy in India. J Trop Pediatr 1997;43(4):199-203.
- Aguilar-Rebolledo F, Sosa-Villalobos R, del Castillo- Troncoso C. Should computed axial tomography of theskull be done in all pediatric patients with epilepsy?. BolMed Hosp Infant Mex 1992;49(12):845-50. (in Spanish)
- Obajimi MO, Fatunde OJ, Ogunseyinde AO, OmigbodunOO, Atalabi OM, Joel RU. Computed tomography and childhood seizure disorder in Ibadan. West 2004;23(2):167-72.
- Wammanda RD, Anyiam JO, Hamidu AU, Chom ND,Eseigbe EE. Computerized tomography of children with seizure disorders. Niger J Clin Pract 2009;12(1):25-8.
- Korff C, Nordli DR Jr. Do generalized tonic-clonic seizures in infancy exist? Neurology 2005, 65:17501753.
- Vanderver A, Chang T, Kennedy C, et al. MR Imaging forthe diagnosis of cerebral dysplasia in new onset seizuresin children. Ann Neurol 2003,54:S114.
- Brain CT scan
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