A Case of Schizencephaly and Septo-Optic Dysplasia Presenting with Anterior Encephalocele

Kaveh FADAKAR, Sahar DADKHAHFAR, Arash ESMAEILI, Zarrintaj KEYHANIDOUST

Abstract


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How to cite this article: Fadakar K, Dadkhahfar S, Esmaeili A, Keyhanidoust Z. A Case of Schizencephaly and Septo-Optic Dysplasia Presenting with Anterior Encephalocele. Iran J Child Neurol Autumn 2012; 6(4):47-50.

 

Abstract

Schizencephaly is a rare central nervous system disorder with variable presentations. Here we report a patient with a huge bilateral schizencephaly and septo-optic dysplasia presenting with anterior encephalocele.

 

References:

  1. Yakovlev PI, Wadsworth RC. Schizencephalies; a study of the congenital clefts in the cerebral mantle; clefts with hydrocephalus and lips separated. J Neuropathol Exp Neurol. 1946 Jul;5(3):169-206.
  2. Yakovlev PI, Wadsworth RC. Schizencephalies; a study of the congenital clefts in the cerebral mantle; clefts with fused lips. J Neuropathol Exp Neurol. 1946 Apr;5:116-30.
  3. Brunelli S, Faiella A, Capra V, Nigro V, Simeone A,Cama A et al. Germline mutations in the homeobox gene EMX2 in patients with severe schizencephaly. Nat Genet. 1996 Jan;12(1):94-6.
  4. Montenegro MA, Guerreiro MM, Lopes-Cendes I,Guerreiro CA, Cendes F. Interrelationship of genetics and prenatal injury in the genesis of malformations of cortical development. Arch Neurol. 2002 Jul;59(7):1147-53.
  5. Granata T, Freri E, Caccia C, Setola V, Taroni F,Battaglia G. Schizencephaly: clinical spectrum, epilepsy, and pathogenesis. J Child Neurol. 2005 Apr;20(4):313-8.
  6. Lee HK, Kim JS, Hwang YM, Lee MJ, Choi CG, Suh DC et al. Location of the primary motor cortex in schizencephaly. AJNR Am J Neuroradiol. 1999 Jan;20(1):163-6.
  7. De Morsier G. [Studies on malformation of cranio-encephalic sutures. III. Agenesis of the septum lucidum with malformation of the optic tract]. Schweiz Arch Neurol Psychiatr. 1956;77(1):267-92.
  8. Hoyt WF, Kaplan SL, Grumbach MM, Glaser JS. Septo-optic dysplasia and pituitary dwarfism. Lancet. 1970 Apr;1(7652):893-4.
  9. Webb EA, Dattani MT. Septo-optic dysplasia. Eur J Hum Genet. 2010 Apr;18(4):393-7.
  10. Ellenberger C Jr, Runyan TE. Holoprosencephaly with hypoplasia of the optic nerves, dwarfism, and agenesis of the septum pellucidum. Am J Ophthalmol. 1970 Dec;70(6):960-7.

Keywords


Encephaloceles; Septo-optic dysplasia; Childhood; Nervous System Diseases; Schizencephaly

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DOI: https://doi.org/10.22037/ijcn.v6i4.2599

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