Incidence and etiology of stroke among hospitalized children, a case-series study
Iranian Journal of Child Neurology,
Vol. 13 No. 1 (2019),
1 January 2019
,
Page 65-70
https://doi.org/10.22037/ijcn.v13i1.18733
Abstract
Objectives: Stroke is a sudden blockage or rupture of brain vessels resulting neural defect or impairment. This study aimed to investigate the incidence and causes of stroke in hospitalized children (Tehran-Iran, 2008-13). Methods: One month to 15 years old admitted children due to stroke entered this case series study. Diagnosis was confirmed with brain imaging. Participants' demographic data, potential risk factors and neuroimaging findings were obtained from Hospital Reporting System. Recorded data were studied and considered regarding to the incidence of stroke and its causes. Indeed we investigated cardiological causes as well as different items related hematological disorders. Results: Of 20000 admitted subjects in Imam Hospital during 5 years, stroke was diagnosed in 15 cases. The incidence among the population study was 0.75 per 100000 children. Stroke was more frequent in males than female ( ). The most common age of stroke was 4-6 years and mean age of stroke was 58.8 months equal to 4.9 years. The most frequent stroke was hemorrhagic stroke (26%), followed by vascular (20%) and coagulopathy disorders (20%). Conclusion: The incidence of stroke in children was 0.75 per 100000. Hemorrhagic stroke due to major trauma, coagulopathy and vasculopathy were observed as most frequent causes that necessitate implementing some strategies for prevention, earlier diagnosis and treatment.
How to Cite
References
Rosa M, De Lucia S, Rinaldi VE, Le Gal J, Desmarest M, Veropalumbo C, Romanello S, Titomanlio L. Paediatric arterial ischemic stroke: acute management, recent advances and remaining issues. Ital J Pediatr. 2015 Dec 2;41:95.
Matta AP, Galvão KR, Oliveira BS. Cerebrovascular disorders in childhood: etiology, clinical presentation, and neuroimaging findings in a caseseries study. Arq Neuropsiquiatr. 2006 Jun;64(2A):181-5.
Chung B, Wong V. Pediatric stroke among Hong Kong Chinese subjects. Pediatrics. 2004 Aug;114(2):e206-12.
Fox CK, Sidney S, Fullerton HJ. Community-based case-control study of childhood stroke risk associated with congenital heart disease. Stroke. 2015 Feb;46(2):336-40.
Mandalenakis Z, Rosengren A, Lappas G, Eriksson P, Hansson P‐O, Dellborg M. Ischemic stroke in children and young adults with congenital heart disease. J Am Heart Assoc. 2016;5:e003071 doi:10.1161/JAHA.115.003071
Domi T, Edgell DS, McCrindle BW, Williams WG, Chan AK, MacGregor DL, Kirton A, deVeber GA Frequency, predictors, and neurologic outcomes of vaso-occlusive strokes associated with cardiac surgery inchildren. Pediatrics. 2008 Dec;122(6):1292-8.
De Veber G. Arterial ischemic strokes in infants and children: an overview of current approaches. SeminThrombHemost 2003;29:567-573.
Eltayeb AA, Askar GA, Abu Faddan NH, Kamal TM. Prothrombotic risk factors and antithrombotic therapy in children with ischemic stroke. TherAdvNeurolDisord. 2015 Mar;8(2):71-81.
Inaloo S, GhofraniM.Stroke in an infant; its association with antiphospholipid antibody and acquired protein C and s deficiencies. Iran J Allergy Asthma Immunol. 2004 Jun;3(2):93-5.
Ghandehari K, Izadi-Mood Z: Incidence and Etiology of Pediatric Stroke in Southern Khorasan. Advanced Research Yeilds Across Atherosclerosis (ARYA) Journal. 2007, 3 (1): 29-33.
Simma B, Martin G, Müller T, Huemer M. Risk factors for pediatric stroke: consequences for therapy and quality of life. Pediatr Neurol. 2007 Aug;37(2):121-6.
Deng Y, Wang Y, Yang W, Yu Y, Xu J, Wang Y, Gao B. Risk factors and imaging characteristics of childhood stroke in China. J Child Neurol. 2015 Mar;30(3):339-43.
Shi KL, Wang JJ, Li JW, Jiang LQ, Mix E, Fang F, Wu HS, Jin X, Jing H, Zou LP. Arterial ischemic stroke: experience in Chinese children. Pediatr Neurol. 2008 Mar;38(3):186-90.
Tavassoli A, Ghofrani M. Clinical Survey of Cerebrovascular Disease in Children. Iran J Pediatr; 2008(18), l1:53-58
Gulati S, Karla V. Stroke in children. Indian J Pediatrics 2003;70:639-648.
Ciccone S, Cappella M, Borgna-Pignatti C. Ischemic Stroke in Infants and Children: PracticalManagement in Emergency. Stroke Res Treat 2011:736965.
- Abstract Viewed: 242 times