risk factors of Febrile Status Epilepticus

Reza Sharafi, Afagh Hassanzadeh rad, Vahid Aminzadeh

Abstract


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Objective: we aimed to investigate risk factors of FSE in children.

Materials and methods: This is an analytic case control study which was conducted on all patients  records with first FS admitted to 17 shahrivar hospital during 2007-2014, Rasht. cases were children aged 6 to 60 months with febrile status epilepticus and controls were children with complex and simple febrile seizures. Data were gathered by a checklist including age, sex, type of milk consuming during first year, temperature, the interval  between fever and seizure, family history of epilepsy and febrile seizure, and prematurity.  Data were reported by descriptive statistics (number, percent, mean, standard deviation) and analyzed by chi square in SPSS 19.

Results: In this study, 756 patients with FS participated including 39 patients with FSE, 194 complex febrile seizure (CFC) and 523 simple febrile seizure(SFC).Most of the patients (57.8%) experienced seizure with low grade fever (<39 c).

 The mean age in SFC group was significantly higher than FSE patients. Significant relation was noted between groups regarding body temperature during seizure (p=0.006), family history of febrile seizure (0.029), family history of epilepsy (p=0.042) and the premature birth (p=0.023)

Significant relation was noted between FSE and CFC groups regarding body temperature during seizure (p=0.004), family history of febrile seizure (0.011), family history of epilepsy (p=0.037), and the premature birth (p=0.025) between FSE and CFC groups.

In Conclusion: According to results, It seems that further investigation which assess these factors can be recommended.


Keywords


febrile status epilepticus, children, epilepsy, risk factor

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References


Nelson Textbook of Pediatric, Kliegman O, Stanton B, Behrman R. 19 th Edition-2011. 2017-2015.

Swaiman's Pediatric Neurology, Swaiman K, Ashwal S, Ferriero D, Schor N, 5th Edition - 2012.1079.

Saba A ,Eric D. M. Febrile Status Epilepticus: Current State of Clinical and Basic Research. 17, (3) 2010, 150–154.

Vezzani A, Aronica E, Mazarati A, Pittman QJ. Epilepsy and brain inflammation. Exp Neurol. 2013 Jun 1;244(244):11-21.

Nelson Textbook of PEDIATRICS, Kliegman O, Stanton B, Behrman R, 18 th Edition-2007 .2473

Graves RC, Oehler K, Tingle LE. Febrile seizures: risks, evaluation, and prognosis. Am Fam Physician. 2012 Jan 15;85(2):149-53.

Hesdorffer DC, Shinnar S, Lewis DV, Nordli DR Jr, Pellock JM, Moshé SL, Shinnar RC, Litherland C, Bagiella E, Frank LM, Bello JA, Chan S, Masur D, Macfall J, Sun S. Risk factors for febrile status epilepticus: a case-control study. J Pediatr. 2013 Oct;163(4):1147-51

Lewis DV, Barboriak DP, MacFall JR, Provenzale JM, Mitchell TV, VanLandingham KE. Do prolonged febrile seizures produce medial temporal sclerosis? Hypotheses, MRI evidence and unanswered questions. Prog Brain Res. 2002; 135:263–78.

Shinnar S, Bello JA, Chan S, Hesdorffer DC, Lewis DV, MacFall J, et al. MR Imaging abnormalities following Febrile Status Epilepticus in Children: The FEBSTAT Study. Neurology. 2012; 79:871–7.

Wallace SJ. Factors predisposing to a complicated initial febrile convulsion. Arch Dis Childhood. 1975; 50:943–7.




DOI: https://doi.org/10.22037/ijcn.v13i1.12099

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