Role of Sexual Function in Prediction of Anxiety, Stress and Depression in Patients with Multiple Sclerosis
International Journal of Applied Behavioral Sciences,
Vol. 5 No. 3 (2018),
8 July 2018
,
Page 27-33
https://doi.org/10.22037/ijabs.v5i3.23755
Abstract
Introduction: Multiple sclerosis is one of the most serious causes of neurodevelopmental disorder in young adults, which can reduce libido, self-esteem and emotional reactions. The aim of this study was to investigate the role of sexual function in predicting anxiety, stress, and depression in patients with multiple sclerosis. Method: The present study was a cross-sectional study. The data of the present study were collected during April to July 2018. For this purpose, 132 patients were selected through purposive sampling method among women with Multiple Sclerosis under the coverage of MS Society of Iran. Demographic checklist, structured clinical interview, self-esteem scale, female sexual function index, and depression, anxiety and stress scale were used to collect data. Data were analyzed by Pearson correlation test, linear regression analysis and step-by-step analysis in SPSS software environment. Results: Data analysis showed that sexual function among patients was a predictor of anxiety and stress (all B's > 2.44; all p's <0.035), but failed to predict depression (p>0.05). Conclusion: The results of this study reflect the difference in the fundamental and multidimensional nature of depression compared to anxiety and stress indices. This findings showed sexual function in predicting depression index is insignificant. In fact, depression index is more complex than anxiety and stress, although they have common pathologic base. The results of this study can be used to design new pathologic approaches
Declaration of Interest: None.
- Multiple sclerosis
- Sexual function
- Depression
- Anxiety
- Stress
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References
- Safizadeh B, Hoshyar R, Mehrpour M, Eftekhar M, Salimi V, Yazdani S, et al. The role of expression and activity of 15-Lipoxygenase isoforms and related cytokines in patients with Multiple Sclerosis and healthy controls. J Neuroimmunol. Elsevier BV; 2018 Dec;325:32–42. [PubMed]
- Gold SM, Willing A, Leypoldt F, Paul F, Friese MA. Sex differences in autoimmune disorders of the central nervous system. Seminars in Immunopathology. Springer Nature America, Inc; 2018 Oct 25. [PubMed]
- Nazareth TA, Rava AR, Polyakov JL, Banfe EN, Waltrip II RW, Zerkowski KB, et al. Relapse prevalence, symptoms, and health care engagement: patient insights from the Multiple Sclerosis in America 2017 survey. Mult Scler Relat Disord. Elsevier BV; 2018 Nov;26:219–34. [PubMed]
- Nery-Hurwit M, Yun J, Ebbeck V. Examining the roles of self-compassion and resilience on health-related quality of life for individuals with Multiple Sclerosis. Disabil Health J. Elsevier BV; 2018 Apr;11(2):256–61. [PubMed]
- Eijkholt M, Sparling A. Health, honesty and happiness: Authenticity and anonymity in social media participation of individuals with multiple sclerosis. Mult Scler Relat Disord. Elsevier BV; 2019 Jan;27:121–6. [PubMed]
- Tan-Kristanto S, Kiropoulos LA. Resilience, self-efficacy, coping styles and depressive and anxiety symptoms in those newly diagnosed with multiple sclerosis. Psychol Health Med. Informa UK Limited; 2015 Jan 14;20(6):635–45. [PubMed]
- Battalio SL, Glette M, Alschuler KN, Jensen MP. Anxiety, depression, and function in individuals with chronic physical conditions: A longitudinal analysis. Rehabil Psychol. American Psychological Association (APA); 2018 Nov;63(4):532–41. [PubMed]
- Nakazawa K, Noda T, Ichikura K, Okamoto T, Takahashi Y, Yamamura T, et al. Resilience and depression/anxiety symptoms in multiple sclerosis and neuromyelitis optica spectrum disorder. Mult Scler Relat Disord. Elsevier BV; 2018 Oct;25:309–15. [PubMed]
- Mosalanejad F, Afrasiabifar A, Zoladl M. Investigating the combined effect of pelvic floor muscle exercise and mindfulness on sexual function in women with multiple sclerosis: a randomized controlled trial. Clin Rehab. SAGE Publications; 2018 May 30;32(10):1340–7. [PubMed]
- Hösl KM, Deutsch M, Wang R, Roy S, Winder K, Niklewski G, et al. Sexual Dysfunction Seems to Trigger Depression in Female Multiple Sclerosis Patients. Eur Neurol. S. Karger AG; 2018;80(1-2):34–41. [PubMed]
- Calabrò RS, Russo M, Dattola V, De Luca R, Leo A, Grisolaghi J, et al. Sexual Function in Young Individuals With Multiple Sclerosis. J Neurosci Nurs. Ovid Technologies (Wolters Kluwer Health); 2018 Jun;50(3):161–6. [PubMed]
- Masmoudi R, Aissi M, Halouani N, Fathallah S, Louribi I, Aloulou J., ... & Frih M. Female sexual dysfunction and multiple sclerosis: A case-control study. Progres en urologie: journal de l'Association francaise d'urologie et de la Societe francaise d'urologie; 2018; 28(11), 530-535. [PubMed]
- Pirnia B, Pirnia K, Mohammadpour S, Malekanmehr P, Soleimani A, Mahmoodi Z, et al. The effectiveness of acupuncture on HPA functional in depressed patients under methadone maintenance treatment, a randomized double-blind sham-controlled trial. Asian J Psychiatr. Elsevier BV; 2018 Aug;36:62–3. [PubMed]
- Pirnia B, Givi F, Roshan R, Pirnia K & Soleimani AA. The cortisol level and its relationship with depression, stress and anxiety indices in chronic methamphetamine-dependent patients and normal individuals undergoing inguinal hernia surgery. Med J Islam Repub Iran. 2016: 30, 395. [PubMed]
- Pirnia B, Pirnia K. Comparison of Two Mindfulness-Based Cognitive Therapies and Acupuncture on the Pain and Depression Index in a Case with Lobular Carcinoma: A Single Case Experimental Study. Int J Cancer Manag. Kowsar Medical Institute; 2018 Jun 4;11(6). [PubMed]
- Sharifi, V., Assadi, S. M., Mohammadi, M. R., Amini, H., Kaviani, H., Semnani, Y & Seddigh, A. (2009). A persian translation of the structured clinical interview for diagnostic and statistical manual of mental disorders: psychometric properties. Comprehensive psychiatry, 50(1), 86-91. [PubMed]
- Babakhanian M, Ghazanfarpour M, Najafi MN, Dizavandi FR, Khadivzadeh T, Safaei M, et al. Psychometric properties of Persian language version of the Female Sexual Function Index (P-FSFI) among postmenopausal women. J Turk Ger Gynecol Assoc. Galenos Yayinevi; 2018 Jun 5. [PubMed]
- Schairer LC, Foley F. Impact of Sexual Dysfunction on Quality of Life in People With Multiple Sclerosis. PsycEXTRA Dataset. APA; 2012. [PubMed]
- Calabrò RS, De Luca R, Conti-Nibali V, Reitano S, Leo A, Bramanti P. Sexual dysfunction in male patients with multiple sclerosis: a need for counseling! Int J Neurosci. Informa UK Limited; 2013 Dec 10;124(8):547–57. [PubMed]
- Salomão P, Navarro P, Romão A, Lerri M, Lara L. Sexual Function of Women with Infertility. Revista Brasileira de Ginecologia e Obstetrícia / Rev Bras Ginecol Obstet. Georg Thieme Verlag KG; 2018 Oct 31. [PubMed]
- Pérez-López FR, Fernández-Alonso AM, Trabalón-Pastor M, Vara C, Chedraui P. Assessment of sexual function and related factors in mid-aged sexually active Spanish women with the six-item Female Sex Function Index. Menopause: Menopause. Ovid Technologies (Wolters Kluwer Health); 2012 Nov;19(11):1224–30. [PubMed]
- Sharifi V, Assadi SM, Mohammadi MR, Amini H, Kaviani H, Semnani Y & Seddigh A. A persian translation of the structured clinical interview for diagnostic and statistical manual of mental disorders: psychometric properties. Compr Psychiatry. 2009. 50(1), 86-91.
- Babakhanian M, Ghazanfarpour M, Najafi MN, Dizavandi FR, Khadivzadeh T, Safaei M, et al. Psychometric properties of Persian language version of the Female Sexual Function Index (P-FSFI) among postmenopausal women. J Turk Ger Gynecol Assoc. 2018 Jun 5.
- Schairer LC, Foley F. Impact of Sexual Dysfunction on Quality of Life in People with Multiple Sclerosis. PsycEXTRA Dataset. 2012.
- Calabrò RS, De Luca R, Conti-Nibali V, Reitano S, Leo A, Bramanti P. Sexual dysfunction in male patients with multiple sclerosis: a need for counseling! Int J Neurosci. 2013 Dec 10;124(8):547–57.
- Salomão P, Navarro P, Romão A, Lerri M, Lara L. Sexual Function of Women with Infertility. Revista Brasileira de Ginecologia e Obstetrícia / Rev Bras Ginecol Obstet. 2018 Oct 31.
- Pérez-López FR, Fernández-Alonso AM, Trabalón-Pastor M, Vara C, Chedraui P. Assessment of sexual function and related factors in mid-aged sexually active Spanish women with the six-item Female Sex Function Index. Menopause. 2012 Nov;19(11):1224–30.
- Whitehouse CE, Fisk JD, Bernstein CN, Berrigan LI, Bolton JM, Graff LA, et al. Comorbid anxiety, depression, and cognition in MS and other immune-mediated disorders. Neurology. 2019 Jan 11;10.
- Ohl K, Tenbrock K, Kipp M. Oxidative stress in multiple sclerosis: Central and peripheral mode of action. Exp Neurol. 2016 Mar;277:58–67.
- Chen Y, Podojil JR, Kunjamma RB, Jones J, Weiner M, Lin W, et al. Sephin1, which prolongs the integrated stress response, is a promising therapeutic for multiple sclerosis. Brain .2019 Jan 17.
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