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Comparing the Effectiveness of Acceptance and Commitment Therapy (ACT), Drug Therapy, and the Combination of These Two Methods in the Treatment of Major Depression

Alireza Mirghiasi, Kourosh Namdari, Saeed Samandari, Nematollah Mortazi
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Abstract

Introduction: A large number of people are afflicted with major depressive disorder, leading to high societal costs. In addition, the treatment remains one of the most challenging and controversial issues in mental health. The main purpose of this study is to compare the effectiveness of acceptance and commitment therapy (ACT), pharmacotherapy, and a blend of the two methods in treating major depressive disorder. Methods: A sample of 60 subjects was selected randomly from the middle-aged patients suffering from major depressive disorder (based on DSM-V criteria) with illness duration of one year that referred to all outpatient clinics of the Modares hospital in Isfahan. The patients were divided into four experimental groups including: acceptance and commitment therapy (ACT), Drug Therapy, blend of the two aforementioned methods and control group. Statistical analysis was conducted using analysis of covariance. Results: Findings showed a significant difference in terms of depression among the three treatment groups. While the mean scores of depression in the posttest were 44.60 for the control group, the results for pharmacotherapy, ACT and combination group were 17.66, 26.53 and 15.13 respectively (p˂0.05). Discussion: Although, Pharmacotherapy and combined treatment are more effective than ACT alone, the combination of ACT and pharmacotherapy is the most effective with longer-lasting results in the treatment of adults with major depressive disorder in middle-aged Iranian patients. Declaration of Interest: None.

Keywords

Major Depressive Disorder;Acceptance and Commitment therapy;Pharmacotherapy

References

Depression: a neglected major illness. Greenberg PE, Stiglin LE, Finkelstein SN, Berndt ER.

J Clin Psychiatry. 1993 Nov; 54(11):419-24.

Depression, low self-esteem and mindfulness. Fennell MJ. Behav Res Ther. 2004 Sep;42(9):1053-67.

Depression: The Disorder and the Burden Indian J Psychol Med. 2010 Jan-Jun; 32(1): 1–2.

Mood instability and impulsivity as trait predictors of suicidal thoughts. Peters EM, Balbuena L, Marwaha S, Baetz M, Bowen R.Psychol Psychotherapy. 2015 Dec 31. doi: 10.1111/papt.12088.

Depression in Older Adults. Amy Fiske, Julie Loebach Wetherell, and Margaret Gatz. Annu Rev Clin Psychol. 2009; 5: 363–389. doi: 10.1146/annurev.clinpsy.032408.153621.

Methodological issues in clinical trials of antidepressant medications: perspectives from psychotherapy outcome research. Gaudiano BA, Herbert JD. Psychother Psychosom. 2005; 74(1):17-25.

Cognitive-behavioral therapy (CBT) versus acceptance and commitment therapy(ACT) for dementia family caregivers with significant depressive symptoms: Results of a randomized clinical trial. Losada A, Marquez-Gonzalez M, Romero-Moreno R, Mausbach BT, Lopez J, Fernandez-Fernandez V, Nogales-Gonzalez C.J Consult Clin Psychol. 2015 Aug;83(4):760-72.

'Third wave' cognitive and behavioural therapies versus other psychological therapies for depression. Hunot V, Moore TH, Caldwell DM, Furukawa TA, Davies P, Jones H, Honyashiki M, Chen P, Lewis G, Churchill R.Cochrane Database Syst Rev. 2013 Oct 18;10:CD008704. Doi.

Hayes SC. (2004). Acceptance & Commitment Therapy: Relational Frame Theory, and the Third Wave of Behavioral and Cognitive Therapies. Behavior Therapy; 35:639-665.

Zettle, Robert D. (2003). Acceptance and Commitment Therapy (ACT) vs. Systematic Desensitization in Treatment of Mathematics Anxiety. The Psychological Record: Vol. 53: Iss. 2, Article 3.

Bach, Patricia; Hayes, Steven C. (2002). The use of acceptance and commitment therapy to prevent the rehospitalization of psychotic patients. Journal of Consulting and Clinical Psychology, Vol v. (5),1129-1139.

Bakhshani N. (1993). Effectiveness of cognitive behavior therapy in anxiety disorders. Persian, dissertation. Tehran: Tehran University of Medical Science: 114,1-80.

Parand A, Khodayarifard M. (2007). Stress and ways to counter it with scale: measuring stressors, stress symptoms, ways of coping. Tehran: University of Tehran Publication.

Cardaciotto LA. (2005). Assessing Mindfulness: The Development of a Bi-Dimensional Measure of Awareness and Acceptance. A thesis for the degree of PhD: Drexel University. Costello, E. J., Mustillo, S., Erkanli, A., Keeler, 0., & Angold, A.

Cacioppo JT, Tassinary LG, Berntson G. (2007). Handbook of psychophysiology. New York: Cambridge University Press.

Hayes SC. (2004). Acceptance & Commitment Therapy: Relational Frame Theory, and the Third Wave of Behavioral and Cognitive Therapies. Behavior Therapy; 35:639-665.

de Jonghe F, Hendricksen M, van Aalst G, Kool 5, Peen V, Van R, et al. Psychotherapy alone and combined with pharmacotherapy in the treatment of depression. Br J Psychiatry 2004; 185:37-45.

Hollon SD, Shelton RC, Davis DD. Cognitive therapy of depression: conceptual issues and clinical efficacy. J Consul Clin Psychol 1993: 61:270-275.

Hayes SC, Bissett RT, Kom Z, Zettle RD, Rosenfarb IS, Cooper LD. (1999). The impact of acceptance versus control rationales - on pain tolerance. The Psychological Record; 49:33-47.

Jam AK, Cooper CL. (2012). Stress and organizational citizenship behaviors in Indian business process outsourcing organizations. IMB Manage Rev;24(3):155-63.

Kath LM, Stichier JF, Ehrhart MG. (2012). Moderators of the negative outcomes of nurse manager stress. J nursing admin.42(4):215-21. PubMed PMID: 22441404. Epub.Eng

Roemer L, Orsillo SM. (2005). An acceptance- based behavior therapy for generalized anxiety disorder. In S.M, Orsillo &, L, Roemer (Eds). Acceptance and mindfulness- based approaches to Anxiety. Conceptualization and treatment. New York: Springer, 213-240.

Koksal, F, & Power, K. G. (1990) Four Systems Anxiety Questionnaire (FSAQ): a self-report measure of somatic, cognitive, behavioral and feeling components. Journal of Personality Assessment. 54(3 & 4): 534-545.

Fava GA, Ruini C, Rafanelli C, Finos L, Conti 5, Grandi S. Six-year outcome of cognitive behavior therapy for prevention of recurrent depression. Am J Psychiatry 2004; 161: 1872-1876.

Fava GA, Ruini C, Rafanelli C, Finos L,Conti 5, Grandi S. Six-year outcome ofcognitive behavior therapy for prevention of

recurrent depression. Am J Psychiatry. 2004Oct;161(10): 1872-6.




DOI: https://doi.org/10.22037/ijabs.v6i1.16765

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