Outcome of breath tests in adult patients with suspected small intestinal bacterial overgrowth.

Johanna Mattsson, Maria Teresa Minaya, Milka Monegro, Benjamin Lebwohl, Suzanne K. Lewis, Peter H.R. Green, Reidun Stenberg

Abstract


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Background

Breath testing is used to detect small intestinal bacterial overgrowth (SIBO) by measuring hydrogen and methane produced by intestinal bacteria.  

Aims

The aim was to investigate breath test outcomes in patients with suspected SIBO and indicative symptoms of SIBO, diagnosed by breath testing.

Methods

A retrospective cross sectional study carried out at Celiac Disease Center at Columbia University in New York of 311 patients undergoing breath testing.

Results

50 % had a positive lactulose breath result and 37 % had a positive glucose breath result (p=0.036). The most common symptom of the patients was bloating. In total 46 % had a positive breath test: 18 % positive for methane, 24 % positive for hydrogen and 4 % positive for both gases (p=0.014). The only statistically significant predictor of positive glucose breath test was increased gas (p=0.028).

Conclusions

Lactulose breath test was more often positive than glucose breath test. Positivity for hydrogen was more common than methane. Bloating was the most frequently perceived symptom. The only statistically significant symptom for a positive glucose breath test was increased gas.


Keywords


Small intestinal bacterial overgrowth; Lactulose breath test; Glucose breath test; Gastrointestinal symptoms; Adults.

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DOI: http://dx.doi.org/10.22037/ghfbb.v0i0.1113

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GHFBB by Gastroenterology and Liver Diseases Research Institute is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

 

PISSN: 2008-2258

EISSN: 2008-4234


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