The effect of hearing Quran verses on reducing chemotherapy-induced nausea and vomiting in cancer patients referring to Imam Hossein Hospital
Background and Objective: Nausea and vomiting are two common and disturbing adverse effect of chemotherapy. There are studies which have used methods or psychological aid such as music therapy to prevent or treat these events. We have evaluated the effect of hearing Quranic verses on decreasing the incidence and grade of these effects.
Method: This was a single group study which evaluated 31 patients who received outpatient chemotherapy in Imam Hossein hospital. The patients received usual premedication for nausea and vomiting during two cycles of chemotherapy and they also listened to Quranic verses in one of these cycles. We filled a questionnaire using international grading system for nausea and vomiting and each case was compared with himself in the two cycles. All ethical issues were observed in this study and the researchers reported no conflicts of interest.
Results: The results showed the about 35% of the patients experienced vomiting during chemotherapy, which decreased to 22% after listening to Quran (p=0.125), which was not statistically significant. Also, there was a 64% decline in the incidence of vomiting (OR=0.36, p=0.03). Listening to Quran significantly decreased the probability of higher grade of nausea in 89% of cases (OR=0.12, p<0.001). About 35.5% of the patients did not have nausea, which increased to 67.7 % after intervention. Also, half of the cases experienced lower grade of nausea in the next cycle after listening to Quran. The grade of nausea did not increase to higher grade after intervention.
Conclusion: Listening to Quran could significantly decrease the incidence of nausea and vomiting. Whether these effects are due to the spiritual effect of Quran or distraction of thought during chemotherapy is not known and should be evaluated in a larger and two-grouped study. Previous studies have shown that listening to Quranic verses has positive effect, including the time when anesthesia is induced. Thus, this technique can be used for controlling the adverse effects of cancer treatment too.
Please cite this article as: Kamian Sh, Tabatabaeefar M. The effect of hearing Quran verses on reducing chemotherapy-induced nausea and vomiting in cancer patients referring to Imam Hossein Hospital. J Res Relig Health. 2019; 5(3):45- 58.doi:https://doi.org/10.22037/jrrh.v5i3.18592
Shafiei N, Salari S, Sharifi M. Camparison between hearing the Quran Arabic Voice and Arabic voice with Persian Meaning on Decreasing the anxiety and Vital Sighns Stabilization of Patients Before induction of Anesthesia. Quran and Medicine. 2017;2(1):11-5. eng.
Karagozoglu S, Tekyasar F, Yilmaz FA. Effects of music therapy and guided visual imagery on chemotherapy-induced anxiety and nausea-vomiting. Journal of clinical nursing. 2013 Jan;22(1-2):39-50. PubMed PMID: 23134272. Epub 2012/11/09. eng.
Silva GJ, Fonseca Mdos S, Rodrigues AB, de Oliveira PP, Brasil DR, Moreira MM. [Use of musical experiences as therapy for symptoms of nausea and vomiting in chemotherapy]. Revista brasileira de enfermagem. 2014 Jul-Aug;67(4):630-6. PubMed PMID: 25271590. Epub 2014/10/02. Utilizacao de experiencias musicais como terapia para sintomas de nausea e vomito em quimioterapia. por.
Lin MF, Hsieh YJ, Hsu YY, Fetzer S, Hsu MC. A randomised controlled trial of the effect of music therapy and verbal relaxation on chemotherapy induced anxiety. Journal of clinical nursing. 2011 Apr;20(7-8):988-99. PubMed PMID: 21385249. Epub 2011/03/10. eng .
Bozcuk H, Artac M, Kara A, Ozdogan M, Sualp Y, Topcu Z, et al. Does music exposure during
chemotherapy improve quality of life in early breast cancer patients? A pilot study. Medical science monitor: international medical journal of experimental and clinical research. 2006 May;12(5):CR200-5. PubMed PMID: 16641876. Epub 2006/04/28. eng.
Tuinmann G, Preissler P, Bohmer H, Suling A, Bokemeyer C. The effects of music therapy in patients with high-dose chemotherapy and stem cell support: a randomized pilot study. Psycho-oncology. 2017 Mar;26(3):377-84. PubMed PMID: 27146798. Epub 2016/05/06. eng.
Burns DS, Meadows AN, Althouse S, Perkins SM, Cripe LD. Differences between Supportive Music and Imagery and Music Listening during Outpatient Chemotherapy and Potential Moderators of Treatment Effects. Journal of music therapy. 2018 Mar 9;55(1):83-108. PubMed PMID: 29471518. Epub 23/02/2018. eng.
Chen SC, Chou CC, Chang HJ, Lin MF. Comparison of group vs self-directed music interventions to reduce chemotherapy-related distress and cognitive appraisal: an exploratory study. Supportive care in cancer: official journal of the Multinational Association of Supportive Care in Cancer. 2018 Feb;26(2):461-9. PubMed PMID: 28799076. Epub 2017/08/12. eng.
Lee EJ, Bhattacharya J, Sohn C, Verres R. Monochord sounds and progressive muscle relaxation reduce anxiety and improve relaxation during chemotherapy: a pilot EEG study. Complementary therapies in medicine. 2012 Dec;20(6):409-16. PubMed PMID: 23131371. Epub 2012/11/08. eng.
Ghiasi A, Keramat A. The Effect of Listening to Holy Quran Recitation on Anxiety: A Systematic Review. Iranian journal of nursing and midwifery research. 2018 Nov-Dec;23(6):411-20. PubMed PMID: 30386389. Pubmed Central PMCID: 6178573.
Effect of Exposure to Quran Recitation on Cell Viability, Cell Migration, and BCL2L12 Gene Expression of Human Prostate Adenocarcinoma Cell Line in Culture. muq-hsme. 2018;5(4):46-52.
Effects of Recitation of Holy Quran on Anxiety of Women before Cesarean Section: A Randomize Clinical Trial. muq-journal. 2010;4(1):15-9.
Under Bethesda Statement on Open Access Publishing (June 20, 2003), cience-research Journal of Pizhūhish dar dīn va salāmat are fully compliant with open access mandates, by publishing its articles under Creative Commons Attribution 4.0 International License (CC BY 4.0). Authors retain copyright of their work and can deposit their publication in any repository. This means that articles can be freely reused by the author and others as long as the article is properly cited. Published articles in Shahid Beheshti University of Medical Sciences Journals can be deposited immediately into an online repository without any cost. This articles can be, printed, archived in a collection, included in course-packs, and distributed without restrictions. Please read the full Creative Commons License for further information.