Comparison of Physical Activity and Body Mass Index in Patients with and without Non-Alcoholic Fatty Liver Disease

Pooneh Dehghan, Mohammad Miwechi, Elham Izadi, Farima Mohammadi, Mohammad Reza Sohrabi

Abstract


164

Background and Objective: The prevalence of Non-Alcoholic Fatty Liver Disease (NAFLD), as one of the health problems, and its complications are increasing. Inadequate physical activity and obesity are the determinants of the incidence of NAFLD. This study aimed to compare physical activity and Body Mass Index (BMI) in both groups of patients with and without NAFLD in Tehran.

Materials and Methods: In this cross-sectional study, 170 outpatients aged 20 to 55 who referred to Taleghani Hospital of Tehran for sonography participated. They were selected using convenience sampling method. Using completing the questionnaires through systematic interviews with individuals, socio-demographic characteristics, complain and the level of  physical activity were assessed. Anthropometric measurements and ultrasound were also performed. Data were analyzed using descriptive methods for descriptive data analysis, T-test and Chi-square tests to compare of the means between groups and to determine the relationship between variables.

Results: Most patients with NAFLD (60%) had intense level of physical activity and only a small percentage of them (11.3%) had low level of physical activity. While in the group of patients with NAFLD, most people (36.7%) had moderate level of physical activity and 28.9% had low level physical activity. The difference between the level of physical activity in the two groups was significant (p=0.001). The mean (SD) BMI of patients with NAFLD was higher than patients without NAFLD (32.8(6.6) vs. 24.4(3)) (p<0.001).

Conclusion: Considering the prevalence of obesity and inadequate physical activity in patients with NAFLD, life style change recommended through designing and implementation of educational interventions to increase their knowledge and improve attitude, also physical activity interventions as option with diet to improve clinical status

Keywords


Non-Alcoholic Fatty Liver Disease; Physical activity; Body Mass Index; Obesity

Full Text:

PDF

73

References


St George A, Bauman A, Johnston A, Farrell G, Chey T, George J. Independent effects of physical activity in patients with nonalcoholic fatty liver disease. Hepatology 2009 Jul;50(1):68-76.

Krasnoff JB, Painter PL, Wallace JP, Bass NM, Merriman RB. Health-related fitness and physical activity in patients with nonalcoholic fatty liver disease. Hepatology 2008 Apr;47(4):1158-66.

Nikroo H, Mohammadian M, Nematy M, Sima HR, Attarzadeh Hosseini SR. The Effect of Diet and Exercise on Improvement of Quality of Life in Patients with Nonalcoholic Steatohepatitis. Journal of Kerman University of Medical Sciences 2015;22(1): 61-72. (Full Text in Persian)

Lankarani KB, Ghaffarpasand F, Mahmoodi M, Lotfi M, Zamiri N, Heydari ST,Fallahzadeh MK, Maharlouei N, Babaeinejad M, Mehravar S, Geramizadeh B. Nonalcoholic fatty liver disease in southern Iran: a population based study. HepatMon 2013 May 23;13(5):e9248.

Nseir W, Hellou E, Assy N. Role of diet and lifestyle changes in nonalcoholic fatty liver disease. World J Gastroenterol 2014 Jul 28;20(28):9338-44.

Hallsworth K, Thoma C, Moore S, Ploetz T, Anstee QM, Taylor R, Day CP, Trenell MI. Non-alcoholic fatty liver disease is associated with higher levels of objectively measured sedentary behaviour and lower levels of physical activity than matched healthy controls. Frontline Gastroenterol 2015 Jan;6(1):44-51.

Zelber-Sagi S, Ratziu V, Oren R. Nutrition and physical activity in NAFLD: an overview of the epidemiological evidence. World J Gastroenterol 2011 Aug7;17(29):3377-89.

Koohpayehzadeh J, Etemad K, Abbasi M, Meysamie A, Sheikhbahaei S, Asgari F, Noshad S, Hafezi-Nejad N, Rafei A, Mousavizadeh M, Khajeh E, Ebadi M, Nakhjavani M, Esteghamati A. Gender-specific changes in physical activity pattern in Iran: national surveillance of risk factors of non-communicable diseases (2007-2011). Int J Public Health 2014 Apr;59(2):231-41.

Moghimi-Dehkordi B, Safaee A, Vahedi M, Pourhoseingholi MA, Pourhoseingholi A, Zali MR. The Prevalence of Obesity and its Associated Demographic Factors in Tehran, Iran. Journal of Health & Development 2012;1(1):22-30. (Full Text in Persian)

Gerber L, Otgonsuren M, Mishra A, Escheik C, Birerdinc A, Stepanova M,Younossi ZM. Non-alcoholic fatty liver disease (NAFLD) is associated with low level of physical activity: a population-based study. Aliment Pharmacol The. 2012 Oct;36(8):772-81.

Da Silva HE, Arendt BM, Noureldin SA, Therapondos G, Guindi M, Allard JP. A cross-sectional study assessing dietary intake and physical activity in Canadian patients with nonalcoholic fatty liver disease vs healthy controls. J Acad Nutr Diet 2014 Aug;114(8):1181-94.

Tsuruta G, Tanaka N, Hongo M, Komatsu M, Horiuchi A, Hamamoto K, Iguchi C, Nakayama Y, Umemura T, Ichijo T, Matsumoto A, Yoshizawa K, Aoyama T, Tanaka E. Nonalcoholic fatty liver disease in Japanese junior high school students: its prevalence and relationship to lifestyle habits. J Gastroenterol 2010 Jun;45(6):666-72.

Kistler KD, Brunt EM, Clark JM, Diehl AM, Sallis JF, Schwimmer JB; NASH CRN Research Group. Physical activity recommendations, exercise intensity, and histological severity of nonalcoholic fatty liver disease. Am J Gastroenterol 2011 Mar;106(3):460-8; quiz 469.

Perseghin G, Lattuada G, De Cobelli F, Ragogna F, Ntali G, Esposito A, Belloni E, Canu T, Terruzzi I, Scifo P, Del Maschio A, Luzi L. Habitual physical activity is associated with intrahepatic fat content in humans. Diabetes Care 2007 Mar;30(3):683-8.

Oh S, Shida T, Yamagishi K, Tanaka K, So R, Tsujimoto T, Shoda J. Moderate to vigorous physical activity volume is an important factor for managing non-alcoholic fatty liver disease: A retrospective study. Hepatology 2014.

Nishioji K, Sumida Y, Kamaguchi M, Mochizuki N, Kobayashi M, Nishimura T,Yamaguchi K, Itoh Y. Prevalence of and risk factors for non-alcoholic fatty liver disease in a non-obese Japanese population, 2011-2012. J Gastroenterol 2015 Jan;50(1):95-108.

Zheng RD, Chen ZR, Chen JN, Lu YH, Chen J. Role of Body Mass Index, Waist-to-Height and Waist-to-Hip Ratio in Prediction of Nonalcoholic Fatty Liver Disease. Gastroenterol Res Pract 2012;2012:362147.

Radu C, Grigorescu M, Crisan D, Lupsor M, Constantin D, Dina L. Prevalence and associated risk factors of non-alcoholic fatty liver disease in hospitalized patients. J Gastrointestin Liver Dis 2008 Sep;17(3):255-60.

Fang JG, Zhu J, Li XJ, Li R, Dai F, Song XM, Chen L, Li F, Chen SY. Epidemiological survey of prevalence of fatty liver and its risk factors in a general adult population of Shanghai]. Zhonghua Gan Zang Bing Za Zhi. 2005 Feb;13(2):83-8.

Khoshbaten M, Fatahi E, Soomi MH,Tarzmani MK, Farhang S, Majidi G, Fatahi V. Clinico-Biochemical comparison of patients with nonalcoholic fatty liver disease and healthy population. Tabibe Shargh 2009;11(1):13-21. (Full Text in Persian)

Hossein-Panah F, Sadeghi L, Rambod M, Foroutan M, Naseri M. Assessing predicting factors in non-alcoholic fatty liver disease (NAFLD) in type 2 diabetes. Pejouhesh. 2006;30(1):9-15.(Full Text in Persian)

Oh S, Tanaka K, Tsujimoto T, So R, Shida T, Shoda J. Regular exercise coupled to diet regimen accelerates reduction of hepatic steatosis and associated pathological conditions in nonalcoholic fatty liver disease. Metab Syndr Relat Disord 2014 Jun;12(5):290-8.


Refbacks

  • There are currently no refbacks.


Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.