The Effectiveness of Cognitive-Behavioral Group Therapy on Improving Quality of Life and Increasing CD4+ Lymphocytes Count in HIV/AIDS Patients in Ahvaz

Shahla Molavi, Naser Seraj-Khorrami, Parvin Ehteshamzadeh, Mehdi Sayyahbargard

Abstract


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Background and Objective: HIV/AIDS is a community medicine issue and has a wide range of negative consequences and challenges. This research aimed to investigate the effect of cognitive-behavioral group therapy on improving the quality of life and increasing CD4+ lymphocyte count in HIV/AIDS patients.

Materials and Methods: The present study was a quasi-experimental study with pre-test and post-test design and control group. The statistical population included HIV/AIDS patients in Ahvaz Behavioral Counseling Center who were selected by simple random sampling method. The sample consisted of 30 patients who were randomly assigned to two groups of cognitive-behavioral therapy and control group. After implementing pre-test on the cognitive-behavioral and control groups, the experimental intervention was administered in 8 sessions for one hour and a half as one session per week for experimental group. Quality of Life Scale, CD4 Index and Demographic Factor Questionnaire were used for data collection. Multivariate analysis of covariance with SPSS software version 22 was used for data analysis.

Results: The results showed that in the experimental group that received cognitive-behavioral therapy, the mean (SD) quality of life score increased from 166.9 (26.7) in the pre-test to 199.5 (21.4) in the post-test (P<0.001) but in control group, the mean (SD) varied from 167.8 (25.5) in pre-test to 168.2 (18.3) in post-test, which was not significant. Also, the mean (SD) of the CD4+ lymphocyte count in the experimental group increased from 247.8 (65.1) in the pre-test to 341.8 (71.1) in the post-test (P<0.001); however, the mean (SD) count in the control group varied from 254.2 (46.2) in the pre-test reached to 256.26 (56.8) in the post-test which was not significant.

Conclusion: It can be concluded that cognitive-behavioral therapy improved the quality of life and CD4+ lymphocyte count in HIV/AIDS patients.

DOI: http://doi.org/10.22037/ch.v7i2.28031


Keywords


Quality of life, Acquired Immunodeficiency Syndrome, Cognitive Behavioral Therapy

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References


CaneT P C. "Facilitating and supporting HIV+ parenthood: Lessons for developing the advocate role of voluntary HIV support services workers." Sexual & Reproductive Healthcare, 2018,16: 186-191.

Zarabadypoor M, Borhanmajaby K, Bagherzade S, Mozafary F. A surveyon the knowledge and attitude of patients referring to the Qazvin dental faculty about AIDS, Journal of Qazvin University of Medical Sciences. 2018, 22 (1), 96: 87-91.

Kennard BD, Brown LT, Hawkins L, Risi A, Radcliffe J, Emslie GJ, Mayes TL, King JD, Foxwell AA, Buyukdura J, Bethel J. Development and implementation of health and wellness CBT for individuals with depression and HIV. Cognitive and behavioral practice. 2014 May 1;21(2):237-46.

Warren N C J, Portillo C, Dawson-Rose and Stringari-Murray S. "HIV Primary Care Curriculum Improves HIV Knowledge, Confidence and Attitudes." The Journal for Nurse Practitioners, Available online. 2018;14(6):113-120.

King B. and Winchester M S. "HIV as social and ecological experience." Social Science & Medicine,2018,208: 64-71.

Oliva J, Roa C, Del Liano J. Indirect costs in ambulatory patient's with-HIV/AIDS in Spain: A pilot study. Pharmacoeconomics. 2003;21(15):1113-21.

Magiorkinis G, Angelis K, Mamais I, Katzourakis A, Hatzakis A, Albert J, Lawyer G, Hamouda O, Struck D, Vercauteren J, Wensing A. The global spread of HIV-1 subtype B epidemic. Infection, genetics and evolution. 2016 Dec 1;46:169-79.

BehmaneshM, TaheryK, Hoseiny S M, BromandZ. Relationship between quality of life and social support in women with HIV / AIDS. Journal of Qazvin University of Medical Sciences, 2012, 3(86): 41-47.

Dianatinasab M, Fararouei M, Padehban V, Dianatinasab A, Alimohamadi Y, Beheshti S, AminiLari Z, AminiLari M. The effect of a 12-week combinational exercise program on CD4 count and mental health among HIV infected women: A randomized control trial. Journal of Exercise Science & Fitness. 2018 Apr 1;16(1):21-5.

Fumaz CR, Gonzalez-Garcia M, Borras X, Muñoz-Moreno JA, Perez-Alvarez N, Mothe B, et al. Psychological stress is associated with high levels of IL-6 in HIV-1 infected individuals on effective combined antiretroviral treatment. Brain, Behavior, and Immunity. 2012;26(4):568-72.

Liu H, Zhao M, Ren J, Qi X, Sun H, Qu L, et al. Identifying factors associated with depression among men living with HIV/AIDS and undergoing antiretroviral therapy: a cross-sectional study in Heilongjiang, China. Health and quality of life outcomes. 2018;16(1):190.

Low Y, Preud'homme X, Goforth HW, Omonuwa T, Krystal AD. The association of fatigue with depression and insomnia in HIV-seropositive patients: a pilot study. Sleep. 2011;34(12):1723-6.

Ironson G, O’cleirigh C, Kumar M, Kaplan L, Balbin E, Kelsch C, et al. Psychosocial and neurohormonal predictors of HIV disease progression (CD4 cells and viral load): a 4 year prospective study. AIDS and Behavior. 2015;19(8):1388-97.

Redman K, Karstaedt A, Scheuermaier K. Increased CD4 counts, pain and depression are correlates of lower sleep quality in treated HIV positive patients with low baseline CD4 counts. Brain, behavior, and immunity. 2018;69:548-55.

Kemmler G, Schmied B, Shetty-Lee A, Zangerle R, Hinterhuber H, Schüssler G, Mumelter B. Quality of life of HIV-infected patients: psychometric properties and validation of the German version of the MQOL-HIV. Quality of Life Research. 2003 Dec 1;12(8):1037-50.

Glasner-Edwards S, Patrick K, Ybarra ML, Reback CJ, Rawson RA, Garneau HC, et al. A cognitive behavioral therapy–based text messaging intervention versus medical management for HIV-infected substance users: Study protocol for a pilot randomized Trial. JMIR research protocols. 2016;5(2):e131.

Kennard BD, Brown LT, Hawkins L, Risi A, Radcliffe J, Emslie GJ, Mayes TL, King JD, Foxwell AA, Buyukdura J, Bethel J. Development and implementation of health and wellness CBT for individuals with depression and HIV. Cognitive and behavioral practice. 2014 May 1;21(2):237-46.

Safren SA, O'Cleirigh CM, Bullis JR, Otto MW, Stein MD, Pollack MH. Cognitive behavioral therapy for adherence and depression (CBT-AD) in HIV-infected injection drug users: a randomized controlled trial. Journal of consulting and clinical psychology. 2012 Jun;80(3):404-15.

Newcomb ME, Bedoya CA, Blashill AJ, Lerner JA, O’Cleirigh C, Pinkston MM, et al. Description and demonstration of cognitive behavioral therapy to enhance antiretroviral therapy adherence and treat depression in HIV-infected adults. Cognitive and behavioral practice. 2015;22(4):430-8.

Solgi Z, Hashemian K, Saeidipour B. The effect of group cognitive therapy on reducing depression in HIV-positive male patients. Psychological studies. 2005; 3(4):105-121.

Blashill AJ, Safren SA, Wilhelm S, Jampel J, Taylor SW, O'Cleirigh C, et al. Cognitive behavioral therapy for body image and self-care (CBT-BISC) in sexual minority men living with HIV: A randomized controlled trial. Health Psychology. 2017;36(10):937-46.

Riley KE, Lee JS, Safren SA. The relationship between automatic thoughts and depression in a cognitive-behavioral treatment for people living with HIV/AIDS: Exploring temporality and causality. Cognitive therapy and research. 2017;41(5):712-9.

Chattopadhyay S, Ball S, Kargupta A, Talukdar P, Roy K, Talukdar A, et al. Cognitive behavioral therapy improves adherence to antiretroviral therapy in HIV-infected patients: a prospective randomized controlled trial from eastern India. HIV & AIDS Review International Journal of HIV-Related Problems. 2017;16(2):89-95.

Safren SA, Bedoya CA, O’Cleirigh C, Biello KB, Pinkston MM, Stein MD, Traeger L, Kojic E, Robbins GK, Lerner JA, Herman DS. Treating depression and adherence (CBT-AD) in patients with HIV in care: A three-arm randomized controlled trial. The lancet. HIV. 2016 Nov;3(11):e529.

Creswell JD, Myers HF, Cole SW, Irwin MR. Mindfulness meditation training effects on CD4+ T lymphocytes in HIV-1 infected adults: A small randomized controlled trial. Brain, behavior, and immunity. 2009 Feb 1;23(2):184-8.

Huguet A, Rao S, McGrath PJ, Wozney L, Wheaton M, Conrod J, Rozario S. A systematic review of cognitive behavioral therapy and behavioral activation apps for depression. PloS one. 2016 May 2;11(5):e0154248.

Soltani E, Shareh H, Bahrainian SA, Farmani A. The mediating role of cognitive flexibility in correlation of coping styles and resilience with depression. Pajoohandeh Journal. 2013 Jun 15;18(2):88-96.


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