Linking Food Industry to “Green Plastics” – Polyhydroxyalkanoate (PHA) Biopolyesters from Agro-industrial By-Products for Securing Food Safety

Keywords: Biopolymers, Polyhydroxyalkanoates, Bioproduction, Feedstocks, Bioprocess Engineering


Aims and Scope

(i) Why do we feel that the issue is important and timely? Research in renewable biopolymers as substitutes for full-carbon-backbone plastics from fossil resources presents a topical R&D field worldwide. This is due to the ongoing depletion of fossil resources, the growing piles of plastic waste and plastic pollution of marine environments, and the need to convert waste streams of different industrial origin in a value-added way. PHA have the potential to replace established petro-plastics both in bulk applications as packaging material and in niche applications, such as the medical, electronical, etc. field. Moreover, the close relation of PHA production and application to the food sector becomes more and more evident. Not only does food production provide numerous (ago) industrial by-products which can, on the one hand, be applied to boost growth kinetics of PHA-accumulation strains, as evidenced in the case of nitrogenaceous whey retentate, silage residues, or shrimps waste, and, on the other hand, act as feedstocks for PHA-biosynthesis under nutritionally unbalanced growth conditions, as demonstrated for carbonaceous surplus materials like whey permeate, lignocellulosics, glycerol, waste lipids, etc. Moreover, PHA are currently investigated as future materials contributing to safe and smart food storage and packaging, as shown by PHA´s beneficial gas barrier properties. Grace to the high compatibility of PHA with numerous organic and inorganic additives, a range of promising PHA-based blend of composite materials are accessible to design novel food packaging materials. This encompasses the application of lignocellulosic filler materials from rice, sugar, or wood production, and even the development of more sophisticated formulations resorting to the incorporation of functional nanoparticles into PHA matrixes. (ii) What communities are expected to participate in the Special Issue? Scientific community; Scholars of higher level; Industrialists (iii) How are the background and expertise of the authors relevant to the proposed Special Issue? List of topics for the Special Issue.



Gajst T, Bizjak T, Palatinus A, Liubartseva S, Krzan A. Sea surface microplastics in Slovenian part of the Northern Adriatic. Marine pollution bulletin 2016; 113 (1-2): 392-399.

doi: 10.1016/j.marpolbul.2016.10.031

Cesa FS, Turra A, Baruque-Ramos J. Synthetic fibers as microplastics in the marine environment: A review from textile perspective with a focus on domestic washings. Sci Total Environ. 2017; 598: 1116-1129. doi: 10.1016/j.scitotenv.2017.04.172

Fonseca MMA, Gamarro EG, Toppe J, Bahri T, Barg U. The Impact of Microplastics on Food Safety: the Case of Fishery and Aquaculture Products. FAO Aquaculture Newsletter 2017; 57: 43-45.

Bouwmeester H, Hollman PC, Peters RJ. Potential health impact of environmentally released micro-and nanoplastics in the human food production chain: Experiences from nanotoxicology. Environ. Sci. Technol. 2015; 49 (15): 8932-8947. doi: 10.1021/acs.est.5b01090

Online resource: Pollack K. Frage und antwort: Wie mikroplastik in den organismus gelangt

Wie-Mikroplastik-in-den-Organismus-gelangt. Accessed October 24th, 2018 (in German)

Wheeler T, Von Braun J. Climate change impacts on global food security. Science. 2013; 341 (6145): 508-513. doi: 10.1126/science.1239402

Myers SS, Smith MR, Guth S, Golden CD, Vaitla B, Mueller N.D. Dangour AD, Huybers P. Climate change and global food systems: Potential impacts on food security and undernutrition. Annu Rev Publ Health 2017; 38: 259-277. doi: 10.1146/annurev-publhealth-031816-044356

Zhu Y, Romain C, Williams CK. Sustainable polymers from renewable resources. Nature. 2016: 540; (7633): 354. doi: 10.1038/nature21001

Akiyama M, Tsuge T, Doi Y. Environmental life cycle comparison of polyhydroxy-alkanoates produced from Degrad. Stab. 2003; 80 (1): 183-194. doi: 10.1016/S0141-3910(02)00400-7

Koller M, Marsalek L, Miranda de Sousa Dias M, Braunegg G. Producing microbial polyhydroxyalkanoate (PHA) biopolyesters in a sustainable manner. New Biotechnol. 2017; 37, 24-38.

doi: 10.1016/j.nbt.2016.05.001

Narodoslawsky M, Shazad K, Kollmann R, Schnitzer H. LCA of PHA production-Identifying the ecological potential of bio-plastic. Chem. Biochem. Eng. Q. 2015; 29 (2): 299-305.

doi: 10.15255/CABEQ.2014.2262

Koller M, Bona R, Braunegg G, Hermann C, Horvat P, Kroutil M, Martinz J, Neto J, Pereira L , Varila P.Production of polyhydroxyalkanoates from agricultural waste and surplus materials. Biomacromolecules 2005; 6 (2): 561-565. doi: 10.1021/bm049478b

Nielsen C, Rahman A, Rehman AU, Walsh MK, Miller CD. Food waste conversion to microbial polyhydroxyalkanoates. Microbial Biotechnology. 2017; 10 (6): 1338-1352. doi: 10.1111/1751-7915.12776

Kwan TH, Hu Y, Lin CSK. Techno-economic analysis of a food waste valorisation process for lactic acid, lactide and poly(lactic acid) production. J. Clean. Prod. 2018; 181: 72-87.

doi: 10.1016/j.jclepro.2018.01.179

Bhatia SK, Shim YH, Jeon JM, Brigham CJ, Kim YH, Kim HJ., Seo HM, Lee JH, Kim JH, Yi DH, Lee YK, Yang YH. Starch based polyhydroxybutyrate production in engineered Escherichia coli. Bioproc. Biosyst. Eng. 2015; 38 (8): 1479-1484. doi: 10.1007/s00449-015-1390-y

Obruca S, Benesova P, Kucera D, Petrik S, Marova I. Biotechnological conversion of spent coffee grounds into polyhydroxyalkanoates and carotenoids. New Biotechnol. 2015; 32 (6): 569-574.

doi: 10.1016/j.nbt.2015.02.008

Kucera D, Benesova P, Ladicky P, Pekar M, Sedlacek P, Obruca S. Production of polyhydroxyalkanoates using hydrolyzates of spruce sawdust: Comparison of hydrolyzates detoxification by application of overliming, active carbon, and lignite. Bioengineeing 2017; 4( 2): 53.

doi: 10.3390/bioengineering4020053

Lammi S, Le Moigne N, Djenane D, Gontard N, Angellier-Coussy H. Dry fractionation of olive pomace for the development of food packaging biocomposites. Ind. Crop. Prod. 2018; 120: 250-261.

doi: 10.1016/j.indcrop.2018.04.052

Keskin G, Kızıl G, Bechelany M, Pochat-Bohatier C, Oner M. Potential of polyhydroxyalkanoate (PHA) polymers family as substitutes of petroleum based polymers for packaging applications and solutions brought by their composites to form barrier materials. Pure Appl. Chem. 2017; 89 (12): 1841-1848.

doi: 10.1515/pac-2017-0401

Rydz J, Musiol M, Zawidlak-Węgrzynska B, Sikorska W. Present and Future of Biodegradable Polymers for Food Packaging Applications. In: Grumezescu AM, Holban AM, Edition: Biopolymers for Food Design, Elsevier Inc., 2018: 431-467. doi: 10.1016/B978-0-12-811449-0.00014-1

Koller M. Poly (hydroxyalkanoates) for food packaging: Application and attempts towards implementation. Appl. Food Biotechnol. 2014; 1 (1): 3-15. doi: 10.22037/afb.v1i1.7127.

Bugnicourt E, Cinelli P, Lazzeri A, Alvarez VA. Polyhydroxyalkanoate (PHA): Review of synthesis, charact-eristics, processing and potential applications in packaging. Express Polym. Lett. 2014; 8 (11): 791-808. doi: 10.3144/expresspolymlett.2014.82

Khosravi-Darani K, Bucci DZ. Application of poly (hydroxyalkanoate) in food packaging: Improvements by nanotechnology. Chem. Biochem. Eng. Q. 2015; 29 (2): 275-285. doi: 10.15255/CABEQ.2014.2260

Koller M, Shahzad K, Braunegg G. Waste streams of the animal-processing industry as feedstocks to produce polyhydroxyalkanoate biopolyesters. Appl. Food Biotechnol. 2018; 5 (4): 193-203.

doi: 10.22037/afb.v%vi%i.18557

Brigham CJ, Riedel SL. The potential of polyhydroxyalkanoates production from food wastes. Appl Food Biotechnol. 2019; 6 (1): 7-18. doi: 10.22037/afb.v6i1.22542

Cinelli P, Mellegni N, Gigante V, Montanari A, Seggiani M, Coltelli B, Bronco S, Lazzeri A. Biocomposites Based on Polyhydroxyalkanoates and Natural Fibres from Renewable Byproducts. Appl Food Biotechnol. 2019; 6 (1): 35-43. doi: 10.22037/afb.v6i1.22039

Chee JY, Lakshmanan M, Jeepery IF, Mohamad Hairudin NH, Sudesh K. The potential application of Cupriavidus necator as polyhydro-xyalkanoates producer and animal feed. Appl Food Biotechnol. 2019; 6 (1): 19-34. doi: 10.22037/afb.v%vi%i.22234

Favaro L, Basaglia M, Gamero Rodriguez JE, Morelli A, Ibraheem O, Pizzocchero V, Casella S. Bacterial production of PHAs from lipid-rich by-products. Appl Food Biotechnol. 2019; 6 (1): 45-52

doi: 10.22037/afb.v6i1.22246

Kumar P, Kim BS. Paracoccus sp. strain LL1 as a Single Cell Factory for the Conversion of Waste Cooking Oil to Polyhydroxyalkanoates and Carotenoids. Appl Food Biotechnol. 2019; 6 (1): 53-60

doi: 10.22037/afb.v6i1.21628

Bustamante D, Tortajada M, Ramon D, Rojas A. Camelina oil as a promising substrate for medium-chain-length polyhydro-xyalkanoates production in Pseudomonas sp. cultures. Appl Food Biotechnol. 2019; 6 (1): 61-70. doi: 10.22037/afb.v6i1.21635

Rebocho AT, Pereira JR, Freitas F, Neves LA, Alves VD, Sevrin C, Grandfils C, Reis MAM. Production of mediumchain length polyhydroxyalkanoates by Pseudomonas citronellol is grown in apple pulp waste. Appl Food Biotechnol. 2019; 6 (1): 71-82. doi: 10.22037/afb.v6i1.21793

Pernicova I, Enev V, Marova I, Obruca S. Interconnection of waste chicken feather biodegradation and keratinase and mcl- PHA production employing Pseudomonas putida KT2440. Appl Food Biotechnol. 2019; 6 (1): 83-90. doi: 10.22037/afb.v6i1.21429