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Cross-Protection Induced by Encephalitis Vaccines against COVID-19 Might be a Reason for Relatively Lower Mortality Rate in Some Countries

Shojiro Katoh, Toshihiko Obayashi, Jegatheesan Saravana Ganesh, Masaru Iwasaki, Senthilkumar Preethy, Samuel Abraham



COronaVIrus Disease 2019 (COVID-19), is an ongoing pandemic attributed to a novel virus SARS‐CoV‐2. The statistics of the incidence and the death rates between nations reveal that there is a discrepancy amongst compared with even those that share their borders. We herein present information from the literature on how cross-protection against COVID-19 conferred by the encephalitis vaccine could be the reason for lower fatality rate in the countries where immunization against encephalitis is widespread or included in national programs. This may pave way for arriving at efficient strategies of prevention as well as vaccine development.


COVID-19; Cross Immunity; Encephalitis vaccine


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DOI: https://doi.org/10.22037/aaem.v8i1.683

DOI (PDF): https://doi.org/10.22037/aaem.v8i1.683.g793

DOI (HTML): https://doi.org/10.22037/aaem.v8i1.683.g806