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The Rate of Catheter-Related Infections using Metal Coated Central Venous Catheters; a Letter to Editor

Seyed Hossein Ardehali, Mona Jahangirian, Alireza Fatemi




Blood infections due to intravenous catheters make up about 10\% -- 15\% of hospital infections (1). In 2009, Centers for Disease Control and Prevention (CDC) reported the rate of blood infections related with using central venous catheter in the intensive care unit (ICU) to be 1.65 in 1000 catheters per day (2). Mortality due to infections related to central venous catheters has been reported to be between 12\% and 25\% in different studies. These infections have increased the duration of hospitalization by 12 days (3, 4). Different approaches have been proposed for reducing these infections, among these approaches using aseptic methods, preventive antibiotics, disposable tools, and training the staff can be pointed out (5-7). Among the methods considered in this regard is using catheters coated with antiseptic agents, antibiotics, and metals such as silver and platinum (8). Some studies have suggested using these methods for reducing the mentioned infections and their consequences; however, their use is not currently agreed upon and their effect on reducing the infections caused by intravenous tools is still being studied.


Central venous catheters; cross infection; infection control; intensive care units; sepsis


Harrison TR, Kasper DL, Fauci AS. Harrison's Principles of Internal Medicine 19th Ed: McGraw-Hill AccessMedicine; 2015.

Control CfD, Prevention. Vital signs: central line–associated blood stream infections—United States, 2001, 2008, and 2009. Annals of Emergency Medicine. 2011;58(5):447-50.

Raad I, Hachem R, Hanna H, Bahna P, Chatzinikolaou I, Fang X, et al. Sources and outcome of bloodstream infections in cancer patients: the role of central venous catheters. European Journal of Clinical Microbiology & Infectious Diseases. 2007;26(8):549.

Marschall J, Mermel LA, Classen D, Arias KM, Podgorny K, Anderson DJ, et al. Strategies to prevent central line–associated bloodstream infections in acute care hospitals. Infection Control & Hospital Epidemiology. 2008;29(S1):S22-S30.

Covey AM, Toro-Pape FW, Thornton RH, Son C, Erinjeri J, Sofocleous CT, et al. Totally implantable venous access device placement by interventional radiologists: are prophylactic antibiotics necessary? Journal of Vascular and Interventional Radiology. 2012;23(3):358-62.

Crnich CJ, Maki DG. Are antimicrobial-impregnated catheters effective? When does repetition reach the point of exhaustion? Clinical infectious diseases. 2005;41(5):681-5.

Hockenhull J, Dwan K, Boland A, Smith G, Bagust A, Dündar Y, et al. The clinical effectiveness and cost-effectiveness of central venous catheters treated with anti-infective agents in preventing bloodstream infections: a systematic review and economic evaluation. NIHR Health Technology Assessment programme: Executive Summaries: NIHR Journals Library; 2008.

Chen Y-M, Dai A-P, Shi Y, Liu Z-J, Gong M-F, Yin X-B. Effectiveness of silver-impregnated central venous catheters for preventing catheter-related blood stream infections: a meta-analysis. International Journal of Infectious Diseases. 2014;29:279-86.


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